Figure_5.tif (2.05 MB)
Allelic association tests between RORA SNPs and asthma.
figure
posted on 2013-04-03, 08:27 authored by Nathalie Acevedo, Annika Sääf, Cilla Söderhäll, Erik Melén, Jami Mandelin, Christina Orsmark Pietras, Sini Ezer, Piia Karisola, Johanna Vendelin, Gustav Boije af Gennäs, Jari Yli-Kauhaluoma, Harri Alenius, Erika von Mutius, Gert Doekes, Charlotte Braun-Fahrländer, Josef Riedler, Marianne van Hage, Mauro D’Amato, Annika Scheynius, Göran Pershagen, Juha Kere, Ville PulkkinenSNPs are represented by dots in relation to their genomic position. Grey-colored dots have a degree of linkage disequilibrium (r2) between 0.40 and 0.60 with the lead SNP (diamond). Recombination rate is indicated as a continuous line. Dashed line represents the significance threshold. (A) Asthma ever up to 4 years in BAMSE; (B) Asthma ever up to 8 years in BAMSE; (C) Physician-diagnosed asthma ever between 5–13 years in PARSIFAL; (D) Physician-diagnosed asthma in the combined dataset.
