Figure_3.tif (525.79 kB)
Acute FGF21 treatment lowers plasma insulin levels.
figure
posted on 2013-09-06, 02:19 authored by Eric S. Muise, Sandra Souza, An Chi, Yejun Tan, Xuemei Zhao, Franklin Liu, Qing Dallas-yang, Margaret Wu, Tim Sarr, Lan Zhu, Hongbo Guo, Zhihua Li, Wenyu Li, Weiwen Hu, Guoqiang Jiang, Cloud P. Paweletz, Ronald C. Hendrickson, John R. Thompson, James Mu, Joel P. Berger, Huseyin MehmetC57BL/6 mice on chow diet were treated with a single dose of vehicle or PEG30-FGF21 Q108 at one of three doses (0.25, 0.75, or 2.5 mg/kg). Plasma insulin levels were measured 24 and 48 hours post dose. Error bars denote standard error. Asterisks denote significant change compared to vehicle treatment within each time point (students t-test p value < 0.05*, p<0.01**).
