A) Visant plot of top 1500 gene connections in 22q11DS Purple module, which is significantly associated with a psychotic disorder (<i>p</i> = .03) and positive symptoms (<i>p</i> = 5.0e-8).

<p>Genes that are the most strongly connected are listed in a larger font than less connected genes. Genes found in the Purple module that overlap with genes in the Salmon module, which was validated in a set of antipsychotic naive schizophrenia patients module [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132542#pone.0132542.ref051" target="_blank">51</a>] are highlighted in red. B) Visant plot of top 1500 gene connections in 22q11DS Royal Blue module, which is significantly associated with an ASD diagnosis. Genes that are most strongly connected are listed in larger font than other, less connected genes. Genes found in the Royal Blue module that overlap with genes in M12 autism-related brain expressed module [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132542#pone.0132542.ref052" target="_blank">52</a>] are highlighted in red.</p>