A–D: Examples of <i>IGF2R</i> allelic expression bias and DMR2 DNA methylation levels for samples from IVF fetuses and controls.

<p>Data points for in-vivo conceived control (AI) fetuses, normal weight in-vitro-fertilization (IVF-n) fetuses and overgrown in-vitro-fertilization (IVF-l) fetuses are shown. (<b>A,C</b>) Allelic expression bias for individual samples from liver and skeletal muscle. The Y axis represents expression from the paternal allele relative to the predominantly expressed maternal allele. (<b>B,D</b>) Corresponding DMR2 methylation levels measured in liver and skeletal muscle of the same individuals. Methylation levels are the mean for 21 CpG sites analyzed by bisulfite pyrosequencing (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059564#pone-0059564-g002" target="_blank"><b>Figure 2</b></a>).</p>