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Aβ accumulation in brains of NEP-deficient mice.

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posted on 2013-02-21, 06:46 authored by Thomas Walther, Doris Albrecht, Matthias Becker, Manja Schubert, Elena Kouznetsova, Burkard Wiesner, Björn Maul, Reinhard Schliebs, Gisela Grecksch, Jens Furkert, Anja Sterner-Kock, Heinz-Peter Schultheiss, Axel Becker, Wolf-Eberhard Siems

ELISA-measured murine Aβ(1–40) accumulation in the cortex of 6-, 12-, and 24-month old mice (−/− = NEP knockout [black bars]; +/+ = wild-type [white bars]); n≥6; average±s.e.m.; all differences were statistically calculated by a Student's t test. **P<0.01, ***P<0.001.

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