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AHL amyloidosis (case 14) (a) Light microscopy.

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posted on 2015-03-26, 03:08 authored by Anne-Laure Poitou-Verkinder, Arnaud Francois, Fanny Drieux, Stéphane Lepretre, Bruno Legallicier, Bruno Moulin, Michel Godin, Dominique Guerrot

Masson trichrome staining. Massive amorphous deposits in the mesangium and extending to the subendothelial space of glomerular capillaries, Bowman’s capsule, the interstitium, the tubular basement membrane and the arterioles. Original magnification, X 20. (b) Apple green birefringence detected under polarized light. Original magnification, X 20. (c) Immunofluorescence microscopy. Monotypic Ig lambda deposits. Equally intense staining for heavy and light chains. (d) Electron microscopy. Non oriented, randomly arranged, 10-nm diameter fibrils. Bar = 1250 nm.

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