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Validation of histone modifications on the KSHV genome in new cases of classic KS tissue.

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posted on 2017-01-24, 04:30 authored by Rui Sun, Xiaohua Tan, Xing Wang, Xiaodong Wang, Lei Yang, Erle S. Robertson, Ke Lan

(A) New classic KS case1 and (B) New classic KS case2. Results of ChIP-qPCR at the region of TR, RTA promoter, miR-cluster, vIRF3 and GAPDH gene (control) in classic KS tissue. Samples prepared from new cases of classic KS tissue were used for ChIP-qPCR assay. ChIP–qPCR data were normalized by the percent input method (signals obtained from ChIP were divided by signals obtained from an input sample). Data are presented as mean±SD. N.A. represents no amplification.

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    vIRF 3 geneunderstanding KSHV epigeneticsAcH 3 histone modificationsH 3K histone modificationsKSHV genomegenome-wide binding sitescell culture systemsRTAH 3KregionAcH 3PELLANA binding siteslandscapeKS tissuesKS tissue samplesSarcoma-Associated Herpesvirus GenomeTRSarcoma Tissues KaposiMCD

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