Two new sesquiterpenoids produced by halophilic <i>Nocardiopsis chromatogenes</i> YIM 90109

<p>Two new germacradiene-type sesquiterpenoids, including 1(10)<i>E</i>,5<i>E</i>-germacradiene-9<i>β</i>,11-diol (or 9<i>β</i>-hydroxyl germacradienol) (<b>1</b>) and 11-hydroxy-1(10)<i>E</i>,5<i>E</i>-germacradien-2-one (2-oxygermacradienol) (<b>2</b>), together with a known geosmin-type sesquiterpenoid (1<i>β</i>,4<i>β</i>,4a<i>β</i>,7<i>α</i>,8a<i>α</i>)-4,8a-dimethyloctahydronaphthalene-1,4a,7(2H)-triol (<b>3</b>), were elucidated by their NMR spectroscopic data, HR–ESI–MS and single-crystal X-ray diffraction from the halophilic strain <i>Nocardiopsis chromatogenes</i> YIM 90109. The antimicrobial activities were evaluated by paper diffusion method.</p>