Two new geranylphenylacetate glycosides from the barks of <i>Cinnamomum cassia</i>

<p>Two new glycosides, cinnacassides F (<b>1</b>) and G (<b>2</b>), with a rare geranylphenylacetate carbon skeleton, were isolated from the barks of <i>Cinnamomum cassia</i>, along with three known analogues, cinnacassides A (3), B (<b>4</b>) and C (<b>5</b>). The structures of the new compounds were elucidated on the basis of extensive NMR spectroscopic analyses and chemical method. Compounds <b>1–5</b> were investigated for their immunomodulatory activities, and compounds <b>1</b>, <b>3</b> and <b>4</b> showed differential immunosuppressive activities against murine lymphocytes.</p>