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Two new flavans from the roots of Dianella ensifolia (L.) DC

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posted on 2017-01-31, 07:42 authored by Ben-Qin Tang, Shu-Sheng Huang, Ye-Er Liang, Jian-Bo Sun, Yan Ma, Bao Zeng, Simon Ming-Yuen Lee, Jian-Lin Lu

Two new flavans, named (2S)-2′,4′-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2′-hydroxy-4′,7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2 displayed cytotoxic effects against cancer cell lines MDA-MB-231, B16-F10, HCT116 and A549.

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