Two new cytotoxic glycosides isolated from the green walnut husks of <i>Juglans mandshurica</i> Maxim.
2016-09-26T12:55:41Z (GMT) by
<p>Two new glycosides including an alcohol glycoside and a phenolic glycoside: hexyl-1-<i>O</i>-<i>α</i>-d-arabinofuranosyl-(1 → 6)-<i>β</i>-d-glucopyranoside (<b>1</b>), 4-hydroxypropiophenone-4-<i>O</i>-<i>β</i>-d-glucopyranosyl(1 → 6)-<i>β</i>-d-glucopyranoside(<b>2</b>), along with six known naphthalenyl glucosides (<b>3</b>–<b>8</b>) were isolated from green walnut husks of <i>Juglans mandshurica</i>, and their structures were elucidated on the basis of spectroscopic studies. All compounds were evaluated for their inhibitory effects on tumour cells (BGC-823, HepG-2, MCF-7). The results showed that new compounds <b>1</b> and <b>2</b> had superior inhibitory activity in comparison with other naphthalenyl glucosides.</p>