Transmission electron microscopy images of chimeric VLP.

<p>Purified preparations of HPV5L1-17RG1 <b>(A)</b>, HPV16L1-17RG1 <b>(B)</b>, HPV1L1-4RG1 <b>(C)</b>, HPV16L1-5L2(aa53-72) <b>(D)</b> and HPV18L1-5L2(aa53-72) <b>(E)</b> were negatively stained and visualized at 30,000-fold magnification. The size bars represent 200nm. +, tubular structures composed of pentamers; *, co-purified baculovirus contaminant.</p>