Total Synthesis of Hyacinthacine A₁ and 3-epi-Hyacinthacine A₁

Total synthesis of hyacinthacine A₁ and its epimer at C3 is described. The synthesis includes a stereocontrolled carboazidation of a chiral allylsilane as a key step. C−Si bond oxidation and reduction of the azide, with ring-closure, complete the total synthesis, which establishes the absolute configuration of 3.