gnpl_a_1448817_sm4596.pdf (2.14 MB)
Three new biflavonoids from the branches and leaves of Cephalotaxus oliveri and their antioxidant activity
journal contribution
posted on 2018-03-16, 06:52 authored by Shu Xiao, Zhen-Qiang Mu, Chun-Ru Cheng, Jie DingThree new biflavonoids, named oliveriflavones A-C (1–3), together with two known flavonoids (quercetin (4) and rutin (5)), were isolated from the endangered plant Cephalotaxus oliveri. The chemical structures of these compounds were elucidated by comprehensive spectroscopic methods including NMR, HRESIMS, IR, UV, and CD spectra. Compounds 1–5 were first isolated from the genus Cephalotaxus. All the compounds were tested for their antioxidant activity. Compounds 4 and 5 showed excellent activity with IC50 values of 0.03 ± 0.06 μM and 0.02 ± 0.10 μM, respectively.