ol6b03300_si_001.pdf (8.77 MB)
Thiophenol-Catalyzed Visible-Light Photoredox Decarboxylative Couplings of N‑(Acetoxy)phthalimides
journal contribution
posted on 2016-12-07, 18:54 authored by Yunhe Jin, Haijun Yang, Hua FuWe have developed
visible-light photoredox decarboxylative couplings
of N-(acetoxy)phthalimides without an added
photocatalyst in which simple and commercially available thiophenols
are used as the effective organocatalysts, and 4-(trifluoromethyl)thiophenol
shows optimal catalytic activity. Three representative decarboxylative
examples were chosen including one amination and two C–C bond
couplings to confirm efficacy of the visible-light photoredox reactions,
and the results exhibited that they performed very well at room temperature.
The interesting discovery should provide a novel and environmentally
friendly strategy for visible-light photoredox transformation of organic
molecules.