sorry, we can't preview this file
lsyc_a_1459722_sm9308.doc (4.11 MB)
TEMPO/CuI synergetic catalyzed oxidative cross-coupling of indoles with benzylamines: Synthesis of bis(indolyl)phenylmethanes
journal contribution
posted on 2018-06-08, 18:37 authored by Meixiang Liao, Xiaoyun Zhang, Pengfei YueTEMPO/CuI was found to be an effective catalyst for the cross-coupling of indoles with benzylic amines affording the corresponding bis(indolyl)phenylmethanes under air atmosphere at room temperature in good to excellent yields. The efficiency, easy workup, simplicity, and chemoselectivity of this protocol provide a green and low-cost procedure for the synthesis of these compounds.