jo8b02153_si_001.pdf (12.74 MB)
Synthesis of 5‑Aryl-3(2H)‑furanones Using Intramolecular Cyclization of Sulfonium Salts
journal contribution
posted on 2018-10-31, 00:00 authored by Sho Inagaki, Kai Saito, Soichiro Suto, Hiromi Aihara, Aoi Sugawara, Satoru Tamura, Tomikazu KawanoBase-induced intramolecular cyclization
of novel (4-aryl-2,4-dioxobutyl)methylphenylsulfonium
salts prepared from the commercially available 1-arylethanone by a
cost-effective process is described in this paper. The reaction was
completed within 10 min to produce a family of 2-unsubstituted 5-aryl-3(2H)-furanones in excellent yield. This procedure is simple,
and can be carried out under mild conditions and an ambient atmosphere.