Supporting information with additional method description and evidences. from Uncovering the mechanisms of Caenorhabditis elegans ageing from global quantification of underlying landscahpe

The detail description of network construction and parameter choice. The Introduction to path integrals method, and the calculation of entropy production rate and flux integrals. The evidences for the network regulations, the gene expression value of ageing and rejuvenation states in the bistable landscape, and the regulation strengths of the oscillation dynamics.