Supplementary Material for: Characterization of the porcine <i>FSCN3</i> gene: cDNA cloning, genomic structure, mapping and polymorphisms

2006-10-27T00:00:00Z (GMT) by Kollers S. Day A. Rocha D.
Fascin 3 (FSCN3)is a testis-specific actin-bundling protein involved in spermatid development. Here we describe the molecular characterisation of the porcine <i>FSCN3</i> gene. The 1,800-bp cDNA sequence contains a 1,497-bp open reading frame encoding a protein of 498 amino acids with a calculated molecular mass of 56.2 kDa and an isoelectric point of 6.82. The porcine FSCN3 protein shares high identity with other mammalian FSCN3. The <i>FSCN3 </i>gene contains seven exons, spans approximately 9 kb, and maps to pig chromosome 18. We also identified 24 DNA polymorphisms.




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