Sub-cellular layout of genes corresponding to peptides present on the kinase substrate array, overlaid with gene expression data from a previous study stimulating human monocytes with N. meningitidis.

The figure shows the sub-cellular location of genes corresponding to peptides present on the kinase substrate array. P-values (top value under each molecule) and fold change (bottom value under each molecule) from a previous study comparing gene expression induced by N. meningitidis with unstimulated controls were overlaid (24). Colored molecules were significantly expressed at FDR 5% in human monocytes stimulated with N. meningitidis compared with control (a), or in IL-10 immunodepleted plasma compared with low LPS plasma (b). Red indicates up-regulated, green indicates down-regulated.