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Silencing of prefrontal cortical neurons with a Green Laser

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posted on 2012-04-21, 09:02 authored by Don CooperDon Cooper, Michael Baratta, Shinya Nakamura

Listen to the popping sound of the neuronal action potentials then when the light turns on the activity stops.

This movie shows for the first time that green laser light can activate virally encoded halorhodopsin to completely silence spontaneous activity from an individual neuron in vivo.  The work was done in the Cooper Optogenetics and Physiology Laboratory at the Institute for Behavioral Genetics/University of Colorado, Boulder. www.neuro-cloud.net

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