Fig 2.TIF (238.97 kB)
Sensitivity analyses using pooled data for associations between genetically predicted BMI and breast cancer risk in the BCAC.
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posted on 2016-08-23, 04:30 authored by Yan Guo, Shaneda Warren Andersen, Xiao-Ou Shu, Kyriaki Michailidou, Manjeet K. Bolla, Qin Wang, Montserrat Garcia-Closas, Roger L. Milne, Marjanka K. Schmidt, Jenny Chang-Claude, Allison Dunning, Stig E. Bojesen, Habibul Ahsan, Kristiina Aittomäki, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W. Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, Natalia V. Bogdanova, Bernardo Bonanni, Anne-Lise Børresen-Dale, Judith Brand, Hiltrud Brauch, Hermann Brenner, Thomas Brüning, Barbara Burwinkel, Graham Casey, Georgia Chenevix-Trench, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Peter Devilee, Thilo Dörk, Martine Dumont, Peter A. Fasching, Jonine Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Henrik Flyger, Florentia Fostira, Marilie Gammon, Graham G. Giles, Pascal Guénel, Christopher A. Haiman, Ute Hamann, Maartje J. Hooning, John L. Hopper, Anna Jakubowska, Farzana Jasmine, Mark Jenkins, Esther M. John, Nichola Johnson, Michael E. Jones, Maria Kabisch, Muhammad Kibriya, Julia A. Knight, Linetta B. Koppert, Veli-Matti Kosma, Vessela Kristensen, Loic Le Marchand, Eunjung Lee, Jingmei Li, Annika Lindblom, Robert Luben, Jan Lubinski, Kathi E. Malone, Arto Mannermaa, Sara Margolin, Frederik Marme, Catriona McLean, Hanne Meijers-Heijboer, Alfons Meindl, Susan L. Neuhausen, Heli Nevanlinna, Patrick Neven, Janet E. Olson, Jose I. A. Perez, Barbara Perkins, Paolo Peterlongo, Kelly-Anne Phillips, Katri Pylkäs, Anja Rudolph, Regina Santella, Elinor J. Sawyer, Rita K. Schmutzler, Caroline Seynaeve, Mitul Shah, Martha J. Shrubsole, Melissa C. Southey, Anthony J. Swerdlow, Amanda E. Toland, Ian Tomlinson, Diana Torres, Thérèse Truong, Giske Ursin, Rob B. Van Der Luijt, Senno Verhoef, Alice S. Whittemore, Robert Winqvist, Hui Zhao, Shilin Zhao, Per Hall, Jacques Simard, Peter Kraft, Paul Pharoah, David Hunter, Douglas F. Easton, Wei Zheng(A) Adjusted for age, study sites, and the first eight principal components. (b) Adjusted for age, study sites, the first eight principal components, and additional breast cancer risk factors: age at menarche, parity, use of contraceptive, use of hormone replacement therapy, breast feeding, and smoking status. Weighted: the BMI-GS was constructed using the additive model weighted by external beta reported from previous literatures. Unweighted: the BMI-GS was constructed using the additive model without any weight.
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breast cancer occurrenceEuropean Descent Background Observationalbreast cancer riskassociationbody mass indexSNPBMIGWASBCACMendelian Randomization Analysesbreast cancer consortiaSingle marker analysesCIbreast cancerpostmenopausal breast cancerGenetically Predicted Body Mass IndexBreast Cancer RiskBreast Cancer Association Consortium
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