Selective immune response of blood group O individuals to increased enteral absorption.

2017-03-21T19:05:06Z (GMT) by Peter Arend
Spontaneous variations in the production of anti-A/B isoagglutinins in individuals suffering from ulcerative colitis and in normal persons were investigated under double-blind conditions. The grade of immunization and dominance of the 7S (IgG) and 19S (IgM) immunoglobulins were determined through the quotients of conglutinin and agglutinin titers at three different temperatures. While the blood group O patients showed a statistically significant stimulation of a 7S (IgG)-exerted anti-B, and less pronounced anti-A reactivity by the non-parametric Wilcoxon procedure, in blood group A plasma, the 7S and 19S (IgM) levels, indicating a reverse tendency, remained within the normal range. The figure is reconstructed from the data published in: Arend, P. & Fehlhaber, G. Varying influence of increased enteral antigen absorption on the behavior of “natural” antibodies in O and A blood group subjects. Comparative blood group serological studies on patients with ulcerative colitis and healthy persons [Article in German]. <i>J Mol Med</i> <i>(Klinische Wochenschrift)</i>. 1969; 47 (10): 535-541. doi:10.1007/BF01715818. <br><br>