pone.0206279.g004.tif (241.1 kB)
Scheme for metabolites of 1a observed with human liver microsomes.
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posted on 2018-11-14, 18:44 authored by Hao Sun, David W. Piotrowski, Suvi T. M. Orr, Joseph S. Warmus, Angela C. Wolford, Steven B. Coffey, Kentaro Futatsugi, Yinsheng Zhang, Alfin D. N. VazScheme for metabolites of 1a observed with human liver microsomes.
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versiondrug pharmacokinetics II2 C 19clearance deuterium isotope effectpharmacokinetic enhancementreaction mechanism influences outcomeresults show3ACYPdockingpharmacokinetic parametersprofilecytochrome P 450Deuterium isotope effectsclearance deuterium isotope effectsclearance isotope effectdeuterationchemotype
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