Fig 5.tif (536.93 kB)
Schematic representation of key different findings compared to corresponding wild-type allele carriers for the mechanisms of increase severe sepsis risk in febrile acute de-compensated cirrhotic patients carrying TLR4+896/A/G or CD14-159C/T variant alleles in current study.
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posted on 2016-11-18, 17:35 authored by Wen-Chien Fan, Chih-Wei Liu, Shuo-Ming Ou, Chia-Chang Huang, Tzu-Hao Li, Kuei-Chuan Lee, Shiang-Fen Huang, Ying-Ying Yang, Yun-Cheng Hsieh, Shie-Liang Hsieh, Ming-Chih Hou, Han-Chieh LinTLR4: gene of toll-like receptor 4; LPS: lipopolysaccharide.
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plasmaHLA-DRImmunologic Dys-Regulations Predictnon-classical monocyte subsetFebrile De-Compensated Cirrhotic Patients Genetic variantsLPS-stimulated TLR 4 expressionvariant allele carrierssepsissCD 14 levelsde-compensated cirrhotic patientsCD 16de-compensated cirrhotic patentsp 38MAPK pathwayTNFnon-classical monocyte subset up-regulated TLR 4-NF
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