Fig 3.TIF (1.03 MB)
Role of HMNE3 in the cell cycle progression of Capan-1 cells.
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posted on 2016-10-19, 17:50 authored by Yong-Chao Ma, Zhi-Xin Wang, Shao-Ju Jin, Yan-Xin Zhang, Guo-Qiang Hu, Dong-Tao Cui, Jiang-Shuan Wang, Min Wang, Fu-Qing Wang, Zhi-Jun ZhaoLogarithmically growing Capan-1 cells were treated with 1.6 μM or 3.2 μM HMNE3 for 24 h. Cell cycle was analyzed by flow cytometry. The statistics of three independent experiments are presented. *, P<0.05 compared with the control group; Student’s t test.
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HMNE 3TUNELHRPtopoisomerase II activityreceptor tyrosine kinasetyrosine kinaseHMNE 3 dosestumor cell proliferationterminal deoxynucleotidyl transferasetopoisomerase II proteinsRTKDNA plasmid pBR 322agarose gel electrophoresisHoechst 33258 fluorescence staining3.2 μ M HMNE 3Human Pancreatic Cancer Cellsnovel bis-fluoroquinolone chalcone-liketopoisomerase IIIC 50 valuecancer cell linesNovel Bis-Fluoroquinolone Chalcone-Liketyrosine kinase activityMTT
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