Rh(I)-Catalyzed Insertion of Allenes into C–C
Bonds of Benzocyclobutenols

Zhao, Chunliang; Liu, Li-Chuan; Wang, Jing; Jiang, Chenran; Zhang, Qing-Wei; He, Wei

doi:10.1021/acs.orglett.5b03518.s001

ol5b03518_si_001.pdf (3.78 MB)

Rh(I)-Catalyzed Insertion of Allenes into C–C Bonds of Benzocyclobutenols

journal contribution

posted on 2016-01-15, 00:00 authored by Chunliang Zhao, Li-Chuan Liu, Jing Wang, Chenran Jiang, Qing-Wei Zhang, Wei He

Herein we report a Rh(I)-catalyzed two carbon insertion into C–C bonds of benzocyclobutenols by employing symmetrical and unsymmetrical allenes. This reaction provides rapid access to alkylidene tetralins bearing two adjacent stereogenic centers in good yields and diasteroselectivities.