Fig 11.TIF (3.93 MB)
Putative model for the Francisella T6SS.
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posted on 2016-09-07, 04:30 authored by Mélanie Rigard, Jeanette E. Bröms, Amandine Mosnier, Maggy Hologne, Amandine Martin, Lena Lindgren, Claire Punginelli, Claire Lays, Olivier Walker, Alain Charbit, Philippe Telouk, Wayne Conlan, Laurent Terradot, Anders Sjöstedt, Thomas HenryThe model was adapted from [13]. The Francisella T6SS is presented in the contraction phase. While the interaction of IglF and IglG was demonstrated in this study, the function and the localization of IglF within the T6SS remain to be determined. While the current knowledge on VgrG and PAAR proteins suggests that the two Francisella homologues may be located at the tip of the T6SS, this remains to be demonstrated.
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Francisella tularensis IglG BelongsFrancisella T 6SSα- helical N-terminal extensionFrancisella Pathogenicity IslandPAAR-Like T 6SS ProteinsUnique N-terminal Extensionnovicida intracellular life cycleN-terminal α- helical extensionT 6SStype VI secretion systemFPIDUF 4280 consensus protein sequenceT 6SS secretionT 6SS effector
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