Proteome database of Aeromonas hydrophila AH1

Resistant to most common antibiotics and cold temperatures, Aeromonas hydrophila is a microorganism that could emerge as a human pathogen of concern. More importantly, its ability to live in aerobic and anaerobic environments endow it with capability in infecting body wounds that would result in morbidity. Finally, ability to use a variety of organic substrates as carbon source further positions A. hydrophila as a potential pathogen given its ability to subsist on small amounts of nutrients in the interstitial fluid that bathe human cells and tissues. This work sought to illuminate the fundamental biology of A. hydrophila AH1 through parsing the UniProt proteome file of the bacterium using an in-house MATLAB software. Specifically, a proteome database comprising protein name, amino acid sequence, number of residues, molecular weight and nucleotide sequence was built that would help guide experiments to deduce the nutritional and environmental conditions that would be most conducive for the growth of this versatile microorganism. Finally, proteomic information would serve as a useful reference for thinking about possible interventions or therapeutic strategies, especially as more research confirms A. hydrophila as an emerging human pathogen.