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Protection against i.p. challenge with different JE virus strains.

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posted on 2016-05-03, 09:09 authored by Lei Cao, Shihong Fu, Xiaoyan Gao, Minghua Li, Shiheng Cui, Xiaolong Li, Yuxi Cao, Wenwen Lei, Zhi Lu, Ying He, Huanyu Wang, Jinghua Yan, George Fu Gao, Guodong Liang

Groups of 10 4-week-old mice were immunized with either (A) 10−3 (2510 pfu), 10−4 (251 pfu) or 10−5 (25 pfu) live attenuated vaccine (LAV) or with (B) 1:5, 1:25 or 1:125 dilutions of inactivated purified vaccine (IPV). Then all mice were challenged i.p. with 500 LD50 JEV P3 or XZ0934 strains.

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