Promoter methylation of <i>OTX2</i> showed differential changes in response to steroid treatment between good and poor responders.

<p>The association of DNAm at 4 CpG sites located within the promoter region of <i>OTX2</i> with time (T<sub>0</sub> vs. T<sub>1</sub>) and responder status were tested using mixed models with age, sex and race being adjusted. Data shown were least square means with standard errors of the methylation% at T<sub>0</sub> and T<sub>1</sub> for good and poor responders respectively. P values were for the responder-specific T<sub>1</sub>-T<sub>0</sub> changes.</p>