Probing Secondary, Tertiary, and Quaternary Structure along with Protein−Cofactor Interactions for a Helical Transmembrane Protein Complex through 1H Spin Diffusion with MAS NMR Spectroscopy

Structure determination of membrane proteins with magic angle spinning NMR is rapidly developing. Probing secondary, tertiary, and quaternary structure along with protein−cofactor interactions through 1H spin diffusion with MAS NMR is demonstrated for a helical transmembrane model protein complex.