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Figure S1 - Pre-Targeting and Direct Immunotargeting of Liposomal Drug Carriers to Ovarian Carcinoma

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posted on 2012-07-26, 00:37 authored by Julia Lehtinen, Mari Raki, Kim A. Bergström, Päivi Uutela, Katariina Lehtinen, Annukka Hiltunen, Jere Pikkarainen, Huamin Liang, Sari Pitkänen, Ann-Marie Määttä, Raimo A. Ketola, Marjo Yliperttula, Thomas Wirth, Arto Urtti

Flow cytometric analysis of cellular affinity shown as mean fluorescence values. The liposomes were incubated with SKOV-3 (A) and SKOV3.ip1 (B–C) cells. In the pre-targeting group, the cells were incubated with neutravidin-cetuximab for 4 h, washed and incubated with biotin-liposomes for 2 h (A–B) or 4 h (C). In the other groups, the cells were incubated with the liposomes for 2 h (A–B) or 4 h (C).

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