Pitucamycin: Structural Merger of a Phenoxazinone with an Epoxyquinone Antibiotic
2010-09-24T00:00:00Z (GMT) by
Chemical profiling of a <i>Streptomyces griseus</i> strain isolated from an old building with moisture damage led to the discovery of two novel phenoxazinones, chandrananimycin D (<b>1</b>) and pitucamycin (<b>2</b>), along with the known grixazone B (<b>3</b>). Pitucamycin represents an unprecedented hybrid molecule composed of a phenoxazinone and an enaminomycin-like epoxyquinone moiety.
CC BY-NC 4.0