ol202786y_si_001.pdf (2.08 MB)
Palladium-Catalyzed Decarboxylation of Allenyl 3-Oxoalkanoates: An Efficient Synthesis of 3,4-Allenyl Ketones
journal contribution
posted on 2012-01-06, 00:00 authored by Baoqiang Wan, Guochen Jia, Shengming MaAn efficient synthesis of 3,4-allenyl ketones via the Pd-catalyzed decarboxylative coupling of the readily available 3-oxoalkanoates is reported. The C–C bond forming reaction occurs under mild conditions producing CO2 as the only byproduct.