jo402024v_si_001.pdf (5.94 MB)
Palladacycle-Catalyzed Methylenecyclopropanation of Bicyclic Alkenes with Propiolates
journal contribution
posted on 2013-11-15, 00:00 authored by Dong-Liang Mo, Teng Yuan, Chang-Hua Ding, Li-Xin Dai, Xue-Long HouAn
efficient way to access functionalized methylenecyclopropanes
has been developed by palladacycle-catalyzed cyclopropanation of bicyclic
alkenes with propiolates in high yields. The structure of the palladacycle
was kept intact in the reaction, shown by 31P NMR spectrum
studies. A rational mechanism has been proposed with a deuterium-labeled
experiment. The usefulness of the functionalized methylenecyclopropanes
has also been demonstrated.