One-Step Ethynylation of Silyl Enol
Ether with Chlorosilylethyne

Arisawa, Mieko; Amemiya, Ryo; Yamaguchi, Masahiko

doi:10.1021/ol026050l.s001

ol026050l_si_001.pdf (39.45 kB)

One-Step Ethynylation of Silyl Enol Ether with Chlorosilylethyne

journal contribution

posted on 2002-06-06, 00:00 authored by Mieko Arisawa, Ryo Amemiya, Masahiko Yamaguchi

In the presence of GaCl₃, silyl enol ethers are ethynylated at the α-carbon atom with chlorotrimethylsilylethyne. This reaction can provide α-ethynylated aryl ketones possessing acidic α-protons without isomerization to conjugated allenyl ketones.