One-Pot Synthesis of Spiro[chromeno[2,3-<i>c</i>]pyrazole-4,3′-indoline]-diones Using Sulfonic Acid Functionalized Nanoporous Silica SBA-Pr-SO<sub>3</sub>H and Study of Their Antimicrobial Properties

<p>A novel and clean one-pot synthesis of spiro[chromeno[2,3-<i>c</i>]pyrazole-4,3′-indoline]-2′,5(6<i>H</i>)-diones via cyclocondensation reaction of isatins, 1,3-cyclohexadiones, and pyrazolone in aqueous media using SBA-Pr-SO<sub>3</sub>H (sulfonic acid-functionalized mesoporous silica) as an efficient heterogeneous solid acid catalyst was reported. The antimicrobial activities of synthesized compounds have been tested.</p>