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Observed outcomes by treatment arm and by benefit/harm subgroup for the SPRINT trial (derivation cohort) and ACCORD-BP trial (validation cohort) when applying models fit by traditional backwards selection.

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posted on 2017-10-17, 17:26 authored by Sanjay Basu, Jeremy B. Sussman, Joseph Rigdon, Lauren Steimle, Brian T. Denton, Rodney A. Hayward

Observed outcomes by treatment arm and by benefit/harm subgroup for the SPRINT trial (derivation cohort) and ACCORD-BP trial (validation cohort) when applying models fit by traditional backwards selection.

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    PLOS Medicine

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    CVD risk reduction benefitsrisk modelsbenefit subgroupCVD eventsblood pressure treatmentrisk reductionNNTBP treatmentrisk increaseACCORD-BP trial dataCVD risk reductionNNHACCORD-BP participant sampleSPRINT trial datarisk differenceCItype 2 diabetesharm subgroupgoal systolic pressure120 mm HgARRselection approachfindings Cox modelsACCORD trials Background Intensive blood pressureARI

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