gnpl_a_1475387_sm0225.pdf (1.46 MB)
New cembrane-type diterpenoids from Bornean soft coral Nephthea sp. with antifungal activity against Lagenidium thermophilum
journal contribution
posted on 2018-05-18, 07:29 authored by Kazuki Tani, Takashi Kamada, Chin-Soon Phan, Charles Santhanaraju VairappanThree new cembrane diterpenes, nephthecrassocolides A-B (1–2) and 6-acetoxy nephthenol acetate (3) along with three known compounds, 6-acetoxy-7,8-epoxy nephthenol acetate (4), epoxy nephthenol acetate (5) and nephthenol (6) were isolated from one population of Nephthea sp. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1–6 were evaluated.