Fig 2.TIF (1.35 MB)
Network-based analysis (SNOW) applied to 46 selected genes (33 recurrent and RARA, PML, and FLT3 genes).
figure
posted on 2016-02-17, 12:10 authored by Mariam Ibáñez, José Carbonell-Caballero, Luz García-Alonso, Esperanza Such, Jorge Jiménez-Almazán, Enrique Vidal, Eva Barragán, María López-Pavía, Marta LLop, Iván Martín, Inés Gómez-Seguí, Pau Montesinos, Miguel A. Sanz, Joaquín Dopazo, José CerveraThe network was complemented with the co-occurrence relationships, in order to summarize the two kind of significant results. Significant network-based analysis genes are coloured in light blue and stroked with a magenta border whether they resulted also significant in co-occurrence analysis. Genes only included by co-occurrence are coloured in magenta. Intermediate genes were painted in white and square shaped. While grey edges represent protein-protein interaction, relationships, broad orange dashed lines describe significant co-occurrences. Moreover, main genes are grouped depending on their biological role (cohesin complex, signalling pathways, spliceosome, RHO-GTPase, retinoic acid regulators and other cellular processes roles).
