pbio.2006348.g005.tif (426.18 kB)
Neo-sex chromosome homology.
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posted on 2018-07-30, 17:23 authored by Shivani Mahajan, Kevin H.-C. Wei, Matthew J. Nalley, Lauren Gibilisco, Doris BachtrogA. Global neo-sex chromosome alignments show large homologous blocks between the neo-sex chromosomes along the long arm of the Y/neo-Y. B and C. Zoom-in of selected homologous regions along the neo-sex chromosomes. Neo-sex-linked regions often contain blocks of homologous genes, reflecting their recent evolutionary origin, but note the dramatic repeat accumulation (shown in gray) at both intergenic and gene regions on the neo-Y, greatly increasing its size.
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sex chromosomesshort-read sequencing technologysex chromosome karyotypesequencing projectsBACDNADrosophila Y chromosomeconsensus validationrepeat-rich Y chromosome41.5 Mbgenome assembliessingle-molecule sequencingchromosomal eventsreference genome assemblycontig formationpericentromeric regionsneo-Y chromosomechromatin interaction mapsY chromosome evolutionY chromosomechromatin conformationtime pointsDrosophila mirandaclone sequencingsequence loss
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