mz8b00321_si_001.pdf (1.29 MB)
Multifunctional Stimuli-Responsive Cellulose Nanocrystals via Dual Surface Modification with Genetically Engineered Elastin-Like Polypeptides and Poly(acrylic acid)
journal contribution
posted on 2018-05-18, 18:41 authored by Jani-Markus Malho, Jérémie Brand, Gilles Pecastaings, Janne Ruokolainen, André Gröschel, Gilles Sèbe, Elisabeth Garanger, Sébastien LecommandouxCellulose
nanocrystals (CNCs) are promising candidates for a myriad
of applications; however, successful utilization of CNCs requires
balanced and multifunctional properties, which require ever more applied
concepts for supramolecular tailoring. We present here a facile and
straightforward route to generate dual functional CNCs using poly(acrylic
acid) (PAA) and biosynthetic elastin-like polypeptides (ELPs). We
utilize thiol-maleimide chemistry and SI-ATRP to harvest the temperature
responsiveness of ELPs and pH sensitivity of PAA to confer multifunctionality
to CNCs. Cryo-TEM and light microscopy are used to exhibit reversible
temperature response, while atomic force microscopy (AFM) provides
detailed information on the particle morphology. The approach is tunable
and allows variation of the modifying molecules, inspiring supramolecular
engineering beyond the currently presented motifs. The surge of genetically
engineered peptides adds further possibilities for future exploitation
of the potential of cellulose nanomaterials.
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SI-ATRPmultifunctional propertiesbiosynthetic elastin-like polypeptidesacidMultifunctional Stimuli-Responsive Cellulose Nanocrystalsparticle morphologysupramolecular engineeringforce microscopyAFMDual Surface ModificationGenetically Engineered Elastin-Like Polypeptidesthiol-maleimide chemistryCNCELPCellulose nanocrystalstemperature responsePAAfuture exploitationpH sensitivitytemperature responsivenesslight microscopycellulose nanomaterials
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