Model validation with experimental results.
(A): Comparison between our model-predicted, spatially averaged PCr/ATP ratio vs VO2 with model predictions from Vendelin et al.  and experimental results from Valdur Saks et al.  (B): Comparison between our model predictions for spatially averaged ADP vs VO2 with predictions from Vendelin et al.’s  zero dimensional model (C): Comparison between model predicted radial profiles of O2 with intracellular PO2 levels calculated by Takahashi et al.  in six different isolated cells.