Minor compounds of the high purity salvianolic acid B freeze-dried powder from <i>Salvia miltiorrhiza</i> and antibacterial activity assessment

<p>The study explored the isolation and characterisation of three compounds of high purity salvianolic acid B freeze-dried powder extracted from <i>Salvia miltiorrhiza</i> Bunge. A new salvianolic acid, salvianolic acid V <b>(2)</b> together with two known compounds <b>(3–4)</b> was identified. The antibacterial activity tests showed that compound <b>2</b> combined with clinical antibiotics such as Levofloxacin or Colistin sulphate together exhibited potent effects against MRSA or <i>Acinetobacter baumanii</i>. This report has considerably extended our knowledge about the diversity and bioactivity of caffeic acid derivatives from <i>S. miltiorrhiza</i>.</p>