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Microwave-assisted synthesis of rhodamine derivatives

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journal contribution
posted on 2018-05-14, 14:14 authored by Fasil Abebe, Treshaun Sutton, Pierce Perkins, Khalil Makins-Dennis, Angela Winstead

The microwave synthesis of 12 rhodamine-derived imines is described. The present work involves condensation of rhodamine hydrazide with various aromatic aldehydes in ethanol under microwave irradiation. The results obtained indicate that, unlike classical heating, microwave irradiation results in higher yields, shorter reaction time, mild reaction condition and simple work-up procedure. The structures of synthesized compounds were confirmed by 1H-NMR, 13C-NMR, FT-IR and high-resolution mass spectra data.

Funding

The authors wish to acknowledge the financial support of the Morgan State University, Chemistry Department, to carry out this research.

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