S1 Table - Microstructural White Matter Changes Underlying Cognitive and Behavioural Impairment in ALS – An In Vivo Study Using DTI

Comparison of ROIs between cognitive subgroups and healthy controls with age, gender and scanner site as covariates. ROI  =  Region of interest; HC  =  Healthy Controls; ALS-ni =  ALS patients without cognitive impairment; ALS-ci  =  ALS-patients with cognitive impairment; FA  =  fractional anisotropy; MD  =  mean diffusivity; AD  =  axial diffusivity RD  =  radial diffusivity; L  =  Left; R  =  Right; CC-B  =  Body of corpus callosum; CST  =  corticospinal tract; ACR  =  anterior corona radiate; SS  =  sagittal stratum including both the inferior longitudinal fasciculus and inferior fronto-occipital fasciculus); CL  =  cingulum; superior longitudinal fasciculus (SLF-L/R); SFOF  =  superior fronto-occipital fasciculus; UF  =  uncinate fasciculus *surviving Bonferroni-Holm correction for multiple comparisons (p<0.05).

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