Microbial transformation of resveratrol by endophyte <i>Streptomyces</i> sp. A12 isolated from <i>Polygonum cuspidatum</i>

<p>Resveratrol (<b>1</b>) undergoes microbial transformation when fermented with <i>Streptomyces</i> sp. A12 to yield 3, 5, 4′-trimethoxy-trans-stilbene (<b>2</b>). The structure of the compound <b>2</b> was elucidated using the modern spectroscopic techniques. This is the first report of the microbial transformation of resveratrol to compound <b>2</b> using the endophyte isolated from <i>Polygonum cuspidatum.</i></p>