jo5b00090_si_001.cif (19.2 kB)
Metal-Free Synthesis of Indole via NIS-Mediated Cascade C–N Bond Formation/Aromatization
dataset
posted on 2015-04-17, 00:00 authored by Yin-Long Li, Jian Li, Ai-Lun Ma, Ya-Nan Huang, Jun DengA novel
rapid synthesis of indoles from N-Ts-2-alkenylanilines
has been described; the reaction involves a NIS-mediated cascade C–N
bond formation/aromatization, and a series of indoles with various
functional groups have been synthesized in good to excellent yields
under mild conditions without any other additives or catalysts.