Fig 8.tif (131.21 kB)
Mechanism of Lef1-mediated Wnt signaling in hypothalamic neurogenesis and anxiety.
figure
posted on 2017-08-24, 17:29 authored by Yuanyuan Xie, Dan Kaufmann, Matthew J. Moulton, Samin Panahi, John A. Gaynes, Harrison N. Watters, Dingxi Zhou, Hai-Hui Xue, Camille M. Fung, Edward M. Levine, Anthea Letsou, K. C. Brennan, Richard I. DorskyLef1-mediated Wnt signaling plays an evolutionarily conserved role in hypothalamic neurogenesis that inhibits anxiety. However, the underlying molecular and cellular mechanisms can vary between organisms.